POLIO (Its facts, causes and risk factors)

(Asifa Abbas, )

• Polio has been traced back almost 6,000 years; great strides have been made in preventing this disease. Polio is an infectious disease caused by viruses, the symptoms may range from non to paralyse and death.

• Not receiving the polio vaccine is the highest risk factor for getting infected with poliovirus; the viruses are only spread human to human by direct and indirect contact.
• Symptoms and signs of polio vary from no symptoms to limb deformities, paralysis, and death.

• Diagnosis of polio is based on the patient's history, physical exam, and ongoing symptoms; the virus may be isolated from the patient's tissues to confirm the diagnosis.
• There is no cure for polio; treatment is mainly supportive and is aimed at limiting or reducing the patient's symptoms.

• For most patients, the prognosis is good because there are few or no symptoms; however, the prognosis declines rapidly as some patients develop more severe symptoms such as limb deformity, paralysis, difficulty breathing, and/or inability to swallow foods.

• It is possible to prevent polio by vaccination; it may be possible to eradicate polio.

• What causes polio?
Polio is caused by small RNA viruses. They are members of the enterovirus group of the Picornavirus family. There are three types of polio viruses; type I is responsible for about 85% of all paralytic infections. These types are antigenically distinct strains of viruses; infection or immunity to one type does not protect against the other two types, however, if immunity is established to one or all of the three strains, immunity is lifelong. The problem that these viruses cause is the destruction of spinal cord cells.

What are risk factors for polio? How does polio spread?
Currently, the World Health Organization (WHO) have certified that the Americas, Western Pacific, and Europe are polio free; other areas have a low incidence of polio, but people in war zones where vaccinations have been interrupted are at a risk getting polio (for example, Afghanistan, Pakistan and Syria). The greatest risk factor for polio is not being vaccinated. People with immunodeficiency (for example HIV, cancer patients), very young individuals, pregnant females, caregivers for polio patients, travellers to areas where polio is endemic, and lab personnel who work with live polioviruses are at increased risk for polio. The poliovirus lives in the throat and in the intestines; polio is spread through contact with the feces or by droplet spread in a sneeze or cough. It can also be spread by an infected person who has contaminated food or fluids by touching or tasting them.

 

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Asifa Abbas
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