Biologics in IBDs like Crohn’s disease

(Eunice Olsen, san)

A prescription drug that’s normally recommended after the preliminary medications, biologics for IBD is developed from living organisms, and help regulate the functioning of immune system, by targeting specific proteins and other causative factors that trigger inflammation. Biologics is widely recommended over corticosteroids & other similar types of drugs, as they can quickly supress the immune system and leave harmful side effects that can be fatal. Although five biologics have been approved by the FDA, Infliximab or Remicade is widely recommended by many experts around the world. This commonly used biologic can effectively suppress the symptoms of Crohn’s disease quickly, no matter whether the prevalent condition of the patient is moderate or severe. Infliximab or Remicade is recommended only when Crohn’s disease patients fail to respond to other standard treatment methods. Remicade can also help heal and reduce the number of perennial fistulas that are commonly found in Crohn’s disease patients. Fistulas often become infected and gets filled in with pus and mucous.

Administered intravenously, Infliximab blocks the effect of Tumour Necrosis Factor alpha. TNF alpha plays a key role in triggering inflammation that aggravates Crohn’s disease conditions. Remicade is widely used to treat rheumatoid arthritis, psoriatic arthritis, ulcerative crohn’s disease, and ankylosing spondylitis, and plaque psoriasis. Those who are allergic to Remicade are advised not to try the medication, instead, have to choose one among the other FDA recommended drug for Crohn’s disease.

Though autoimmune disease are normally incurable, Remicade can help reduce their symptoms, including pain and inflammation, and thus start making a positive difference within just 48 hours. However the effect may not be the same for a few patients, the reason why they might have to wait several weeks. Therefore patience, perseverance, and strong adherence to the treatment regime are extremely important to receive best results.

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Eunice Olsen
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